Once you’ve finished stamping your way to brighter and plumper skin, follow the below cleaning and storage instructions:
A step-by-step guide to using your system safely and effectively.
Contents
01
Recommendations of use
02
Get To Know Your Micro-Infusion Device
03
Serum info & full ingredients
04
Safety Guidelines
05
Pre Treatment
06
How To Micro-Infuse
07
Post Treatment Care
08
Post Treatment Precautions
09
How To Clean & Storage
10
FAQ's
1
Recommendations of use
This Instruction Manual provides important information about the safe use of the SkinOS PDRN Micro-Infusion System. It is the responsibility of the user to carefully read all information presented in this manual before starting treatment with the SkinOS™ Micro-Infusion System. It is always the user’s responsibility to follow the instructions contained in this manual.
It is also the responsibility of the user/purchaser to be aware of local laws and regional restrictions regarding microneedling. Please read this manual carefully and in full before use.
Keep this manual for future reference so it is always accessible.
DISCLAIMER
SkinOS and its representatives hold no responsibility for treatment outcomes, as individual results may vary. The SkinOS PDRN Micro-Infusion System is not designed to diagnose, treat, or cure any medical conditions, and should only be used as directed.
To ensure a safe and effective experience, please read and understand the following disclaimers before using the SkinOS PDRN Micro-Infusion System.
To ensure a safe and effective experience, please read and understand thefollowing disclaimers before using the SkinOS PDRN Micro Infusion System.
Our Micro-Infusion device allows you to “stamp” your skin with 24K gold plated needles that are thinner than human hair.
This delivers a powerful one-two-punch:
- It “tricks” your skin into activating your body’s natural healing process.
- It creates invisible channels in the top layer of skin. Then infuses ingredients into your skin through to accelerate absorption and results.
Our SkinOS PDRN Renewal Serum is formulated specifically for use with the SkinOS Micro-Infusion System. Each ampoule delivers a potent blend of active ingredients designed to target visible skin concerns such as uneven texture, fine lines, acne scars, and hyperpigmentation. The lightweight formula absorbs quickly, working beneath the skin’s surface to promote renewal, hydration, and overall radiance.
The serum is dermatologically tested, fragrance-free, and suitable for all skin types.
Do+ Safety Guidelines
- Consult your dermatologist before use if you suffer from any skin condition.
- Ensure your hands are clean before and during treatment; you may wear gloves if you feel safer doing so.
- Always perform a patch test on an area of your skin that isn't too exposed prior to treatment.
- Sanitize your hands and the device before use.
- Wash your face with water if there's any bleeding.
- Wear high protection sunscreen after treatment.
- Always store the device in the supplied box for maximum hygiene and safety.
- Always sterilize the device after treatment.
- Open and use a new needle head cartridge for every treatment and attach it to your device. Do not touch the tip of the needles.
Don’t+ Safety Guidelines
- Don’t reuse the needle head.
- Don’t use topical retinoids before treatment (at least for a day).
- Avoid stamping directly on active breakouts.
- Avoid delicate areas (e.g., eye area).
- Don’t proceed if skin is irritated or inflamed.
- Don’t use just any serum; only use those formulated for micro-infusion.
- Don’t go over one area too many times.
- Don’t apply too much force or pressure.
- Don’t use comedogenic serums or oils during/after treatment.
- Avoid use on raised scars such as keloids.
- Don’t use active skincare until after day 3 of treatment.
- Don’t expose the treated area to the sun up to 72 hours after treatment.
- Tie hair back and keep it away from face.
- Cleanse skin twice to remove all traces of makeup and lotions. Any dirt, oil, or stray hairs that touch your face can increase the risk of irritation or infection.
- Prepare the treatment area, sterilise the surface you are using, and keep alcohol disinfectant close by. If you touch a serum bottle, brush, or anything other than your skin and the device during the treatment, you could be causing cross-contamination.
Pour serum into device
- Twist open the chamber of the device
- Break the seal of the serum vial, remove rubber stopper and pour serum into the chamber of the device.
- Place the lid back on the device and twist to close tight
Turn device upside down
- Leave the device upside down for 2 minutes.
- During this time, wash your face and make sure your hands are clean.
- It's essential to leave the device for long enough so the serum can make it's way down into the head of the device.
Start micro-infusing
- Once the serum has had enough time to make its way into the needles, you can take off the lid and start microinfusing
- Start at the center of your face and work your way outward to cover the full face.
- Stamp with 50% overlap.
- If you notice the serum isn't coming through the needles, try tilting your head back slightly or angling the device toward the ceiling to guide the serum downward.
Leftover Serum
- Take all the leftover serum from the device and pat it onto your face and neck
- Leave the serum on overnight so your skin can drink up all those nourishing ingredients
Clean & Moisturize
- The day after treatment, wash your face with a gentle cleanser and apply a nourishing moisturizer.
Avoid Makeup
- Skip makeup for as long as you can, but at minimum, at least 24 hours. If applying makeup is unavoidable, try to use one specifically for post-treatments or for sensitive skin to avoid irritation.
Avoid Acids
- Keep in mind, anything you put on your skin after using the micro-infusion will absorb more easily, so it’s important to keep the skin clean and use products that don’t have harsh ingredients (no acids!).
Avoid Pools
- Avoid swimming, saunas and steam rooms for at least 24 hours post-treatment.
Reduce Redness
- Users may experience minor redness and irritation after the procedure but should quickly subside. Skin may experience mild swelling, peeling or flaking. You can minimize these effects by keeping the skin moisturized, which will reduce shedding and alleviate tightness.
Avoid Sweat
- No exercising or strenuous activity for the first 24 hours post-treatment. Sweating and gym environments are harmful, rife with bacteria, and may cause adverse reactions.
Don't Touch
- Avoid touching your face, especially with dirty hands that haven’t been sanitized.
Skip washing after the treatment
- Avoid washing your face the day of treatment.
Avoid makeup
- Skip makeup for minimum 24 hours. If applying makeup is unavoidable, try to use one specifically for post-treatments or for sensitive skin to avoid irritation.
Avoid sun exposure
- Avoid direct sun exposure 24–48 hours after treatment.
- Apply a high protection sunscreen when going outdoors, and avoid prolonged sun exposure.
- Use good quality non-comedogenic sunscreen if going in the sun.
Skip skincare products
- Avoid applying skincare products containing fragrances, active ingredients or acids such as Alpha Hydroxy Acids, Beta Hydroxy Acid, Retinol (Vitamin A), Vitamin C or anything perceived as ‘active’ skincare including scrubs or toners for at least 2–3 days post-treatment, as it may cause irritation.
Avoid exfoliation
- Avoid exfoliating products for 2–3 days after treatment because they can be abrasive on skin when it is in that kind of condition.
Cleaning
- Twist off the needle head with the cap attached and safely dispose.
- Wash the chamber out with water and gentle cleanser.Let the device air dry completely, on a clean surface, before packing away.
- Open a brand new needle head packet and attach the needle head onto the device. Ensure hands are clean and don’t open the cap of the needle head.
Storage
- Store the device in the box until your next use and between treatments.
- Keep device and needle heads in a safe, dry environment away from heat, humidity and bacteria. Bathroom storage is not recommended.
- Store away out of reach from children.
How does the 90 day money back guarantee work?
You have 90 days to try our PDRN Micro-Infusion System and see how it works for your skin. If you don’t notice any improvement in your skin’s appearance, simply contact us and we’ll gladly refund your money. To qualify, you’ll just need to provide before-and-after photos after each application within the 60-day period.
How do I clean the device?
Once you’ve finished stamping your way to brighter and plumper skin, follow the below cleaning instructions:
- Twist off the needle head with the cap attached and safely dispose.
- Wash the chamber out with water and gentle cleanser.
- Let the device air dry completely, on a clean surface, before packing away.
- Open a brand new needle head and attach the needle head onto the device. Ensure hands are clean and don’t open the cap of the needle head.
When will I see results?
Most people notice their skin looking more hydrated and radiant after the first few applications. Improvements in smoothness and texture often appear within 2–4 weeks. For deeper results — like fading dark spots, reducing fine lines, and improving scars — you can expect visible changes after completing a 6–12 week cycle.
Because the micro-infusion system works at the cellular level, your results continue to build with consistent use.
Is it suitable for all skin types?
Yes — the PDRN Micro-Infusion System is suitable for all skin types, including normal, dry, oily, and combination. It’s designed to be gentle and effective, even for sensitive skin. If you have specific skin concerns such as eczema, rosacea, or severe acne, we recommend consulting with your dermatologist before purchasing to ensure it’s right for you.
Is there any down-time?
There’s very little downtime. You may notice mild redness or sensitivity right after application, similar to a light sunburn, which usually fades within 12–24 hours.
We recommend avoiding makeup, exfoliants, and strong active ingredients (like retinol, AHAs, BHAs, or vitamin C) for the first 24 hours to allow your skin to recover and maximize results. After that, you can return to your usual skincare routine.
Most people go back to daily activities immediately, with visible glow and minimal disruption.
Can you use it around the eyes and neck?
Yes, the SkinOS Micro-Infusion System can be safely used on the neck and décolletage to target fine lines, wrinkles, and uneven texture in those areas.
For the eye area, avoid direct use on the eyelids or too close to the lash line. Instead, focus on the under-eye and outer corners (crow’s feet), where the skin is thinner but can still benefit from infusion. Always use gentle pressure and follow instructions carefully.
How often can I do the treatment?
We recommend a PDRN Micro-Infusion application every 2 weeks for the best results!
How does it compare to Rejuran?
Rejuran is an in-clinic injectable treatment that also uses PDRN (Salmon DNA) to repair and regenerate skin. It’s highly effective but requires medical administration, downtime, and costs hundreds of dollars per session.
The SkinOS PDRN Micro-Infusion System offers an at-home alternative inspired by the same ingredient. Using ultra-fine micro-needles, it helps PDRN absorb beneath the skin’s surface without injections, pain, or long recovery times. This makes the benefits of micro-infusion more accessible, affordable, and repeatable from home.
Are there any side effects?
The SkinOS Micro-Infusion System is intended for at-home use and is generally well tolerated. Some people may experience mild redness, sensitivity, or slight swelling similar to a light sunburn. These effects are temporary and usually fade within 12–24 hours.
To protect your skin, avoid makeup, exfoliants, and strong actives (like retinol, AHAs, BHAs, or vitamin C) for the first 24 hours. Most people return to daily activities right away.
If you have a skin condition or are unsure if this system is right for you, we recommend consulting your healthcare provider before use. A patch test 24 hours prior to treatment is also advised. Serious side effects are rare when used as directed.
Can I use PDRN if I'm allergic to fish?
No — PDRN (Polydeoxyribonucleotide) is derived from salmon DNA. If you have a fish allergy, we do not recommend using this system, as it may trigger a reaction.
Your safety is our priority. If you have concerns about allergies or sensitivities, please consult your healthcare provider before use.
Do you ship internationally?
Yes, we ship worldwide. We have 5-12 day shipping times depending on your location.