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PDRN Micro-Infusion System
Skincare that finally absorbs.
SkinOS is an at-home micro-infusion system that pairs ultra-fine cosmetic touchpoints with a PDRN serum, helping active ingredients absorb more effectively than a topical applied on its own. For smoother, plumper, more radiant-looking skin over time, without the clinic, or the complexity.
Suited to: All skin types, including sensitive skin.
90 Day Money Back Guarantee
We’re confident you’ll love your results. If not, contact our team during your risk-free trial and we’ll handle the rest!
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Most Serums Never Get Past the Surface
As skin matures, its outer barrier becomes less efficient at absorbing what's applied on top. That's not a product problem - it's a delivery one. A great serum can only do so much if most of it sits on the surface.
SkinOS uses ultra-fine cosmetic touchpoints to create temporary micro-channels in the skin's surface, helping a PDRN serum absorb more effectively than it would on its own. For smoother, plumper, more radiant-looking skin over time.
Designed for absorption. Gentle enough for home.
Excellent · 1,000+ Reviews · ★★★★★
What Customers Are Saying
Janet, 47
"Feels like my skin again"
"Perimenopause did a number on my skin texture and I felt like nothing was helping. This is the first thing in a while that made my skin feel hydrated and look a little more even. Comfortable and easy to use at home too."
Susan, 59
"My skin texture is just nicer"
"The lines around my mouth had been bothering me. After 5 treatments the area feels softer and my skin texture overall is just nicer. So glad I tried this."
Linda, 49
"Softened so much, especially when I smile"
"To be honest I didn't expect much. The look of the lines around my eyes has softened, especially when I smile, and my cheeks look smoother. Placed another order."
Carol, 61
"Worth being patient for"
"I almost gave up around week three because I wasn't seeing much. Glad I kept going. By the end of the full routine my cheeks felt firmer and the skin around my jaw looked a bit more lifted to me. Will repurchase"
Diana, 52
"Genuinely surprised by the difference"
"I did the full 3 months and the difference around my neck is really there. My skin looks smoother and a bit more like itself. Happy I tried it."
Margaret, 40
"My makeup sits better now"
"I'd noticed my foundation settling into the creases on my forehead. After a couple of months using this a few nights a week, the skin there feels smoother and my makeup goes on more evenly. Small thing but it made me happy."
More Than a Serum. Simpler Than a Clinic Visit.
SkinOS works in two parts. Ultra-fine cosmetic touchpoints create temporary micro-channels in the skin's outer layer - invisible, comfortable, and gone within hours. Through those channels, a PDRN serum absorbs more effectively than a topical applied on its own.
PDRN (polydeoxyribonucleotide) is a salmon-derived compound widely used in skincare, valued for supporting the look of smoother, firmer, more radiant skin.
A more intentional step than a serum - done privately, at home, on your own schedule.
Why PDRN, and Why Now
A Studied Compound
PDRN is a salmon-derived compound that's been studied for years and is widely used in aesthetic skincare for its appearance benefits.
Used in Clinics Worldwide
PDRN is used in aesthetic skincare clinics across Korea and Europe to support skin quality, texture, and hydration. Clinic sessions can cost thousands of dollars.
At Home, the Smart Way
SkinOS combines a PDRN serum with at-home micro-infusion. The device helps the serum absorb more effectively than a topical alone. Five minutes, every two weeks, in your bathroom.
Built for Mature Skin
Mature skin needs more than topical moisture. PDRN is one of the few studied ingredients associated with supporting the look of skin quality, hydration, and texture as skin's natural renewal slows.
How to use your micro-infusion system
Prepare your device
Fill the chamber with one ampoule of serum, attach the single-use head, and let it sit upside down for 1–2 minutes while you cleanse.
Infuse your skin
Gently stamp the device across your face, focusing on areas of concern. The ultra-fine cosmetic-grade touchpoints create temporary micro-channels that help the serum absorb.
See your results
With consistent use, your skin can appear smoother, more radiant, and refreshed over time.
Powered by proven ingredients
Salmon PDRN
Helps support skin repair and renewal, improving the look of wrinkles, elasticity, and overall radiance.
Peptides
Support collagen and elastin, helping smooth texture and soften the appearance of fine lines and skin texture.
Niacinamide
Helps brighten the look of dark spots, even skin tone, and strengthen the skin barrier for a smoother feel.
Hyaluronic Acid
Delivers deep hydration to plump skin and reduce the appearance of dryness and dullness.
Frequently Asked Questions
How does micro-infusion work?
The device uses ultra-fine cosmetic-grade touchpoints to gently stamp the skin's surface, creating temporary micro-channels that help active ingredients like PDRN absorb more effectively. It's a gentle method designed to enhance product absorption and help skin look refreshed, with minimal downtime
What's included?
Each kit includes:
6 Week Supply: 3 sterile heads and 3 serum vials, providing 3 treatments.
12 Week Supply: 6 sterile heads and 6 serum vials, providing 6 treatments.
Each head and serum is intended for a single application every 1-2 weeks and should not be reused.
How quickly can I expect improvements?
Many people say their skin looks fresher and more radiant after the first few uses. Improvements in hydration, texture, and glow often become noticeable with regular use. Over time, users also report their skin looking smoother, more even-toned, and healthier overall.
Because micro-infusion supports the skin’s natural renewal process, results can continue to build gradually over time.
How does the 90 day money back guarantee work?
You have 90 days to try the system. If you're not satisfied, simply contact our team within the 90-day period and we'll arrange your refund.
How do I clean the device?
After each use, follow these cleaning steps, follow the below cleaning instructions:
- Twist off the head with the cap attached and safely dispose.
- Wash the chamber out with water and gentle cleanser.
- Let the device air dry completely, on a clean surface, before packing away.
- Open a brand new head and attach the head onto the device. Ensure hands are clean and don’t open the cap of the head.
How quickly can I expect improvements?
Many people say their skin looks fresher and more radiant after the first few uses. Improvements in hydration, texture, and glow often become noticeable with regular use. Over time, users also report their skin looking smoother, more even-toned, and more radiant overall.
Because micro-infusion supports the skin's natural renewal process, results can continue to build gradually over time.
Is it suitable for all skin types?
Yes — the PDRN Micro-Infusion System is suitable for all skin types, including normal, dry, oily, and combination. It’s designed to be gentle and effective, even for sensitive skin. If you have specific skin concerns such as eczema, rosacea, or severe acne, we recommend consulting with your dermatologist before purchasing to ensure it’s right for you.
Is there any down-time?
There’s very little downtime. You may notice mild redness or sensitivity right after application, similar to a light sunburn, which usually fades within 12–24 hours.
We recommend avoiding makeup, exfoliants, and strong active ingredients (like retinol, AHAs, BHAs, or vitamin C) for the first 24 hours to allow your skin to recover and maximize results. After that, you can return to your usual skincare routine.
Most people go back to daily activities immediately, with visible glow and minimal disruption.
Can you use it around the eyes and neck?
Yes, the SkinOS Micro-Infusion System can be used on the neck and décolletage, areas often associated with fine lines and uneven texture.
For the eye area, avoid direct use on the eyelids or too close to the lash line. Instead, focus on the under-eye and outer corners (crow’s feet), where the skin is thinner but can still benefit from infusion. Always use gentle pressure, follow instructions carefully, and patch test first.
How often can I do an application?
We recommend a PDRN Micro-Infusion application every 2 weeks for the best results!
How does it compare to Rejuran?
Rejuran is an in-clinic treatment that also uses PDRN. SkinOS offers an at-home option using the same family of PDRN ingredient in a topical serum, paired with micro-infusion to help it absorb - without injections or clinic visits.
Can I use PDRN if I'm allergic to fish?
No — PDRN (Polydeoxyribonucleotide) is derived from salmon DNA. If you have a fish allergy, we do not recommend using this system, as it may trigger a reaction.
Your safety is our priority. If you have concerns about allergies or sensitivities, please consult your healthcare provider before use.
Do you ship internationally?
Yes, we ship worldwide. We have 5-12 day shipping times depending on your location.
- IFIvana F.9 months agoRated 5 out of 5 stars6 weeks, clearer skin
I’ve been using this system for about six weeks now, and I can honestly say the results have surprised me. The process itself is straightforward , cleanse, use the micro-infusion device with the serum, then let the skin recover overnight. The first couple of times I noticed a bit of redness, but it always faded by the next morning. Week by week my skin has become smoother, my tone is more even, and I feel like I’ve got a natural glow again. It’s such a good feeling to see progress every time I look in the mirror.
- NONatalia O.9 months agoRated 5 out of 5 starsResults results results
I’ve been using this treatment consistently for the past month, following the instructions exactly, cleansing first, then using the micro-infusion system with the serum once a week. At first I was a little nervous about the process, but it’s surprisingly gentle and only left my skin a little pink for a few hours. After the second session I already noticed my skin feeling smoother, and now, after four treatments, the difference is clear. My pores look smaller, the texture is more even, and I have this healthy glow that I’ve never been able to achieve with regular creams alone. It honestly feels like bringing a professional treatment into my own home.
- AAnya9 months agoRated 5 out of 5 starsFinally seeing real results in my skin
My skin feels smoother and looks brighter after a few weeks of use. The difference in tone and texture is really noticeable, and even my friends have commented on the glow. I finally feel confident without layering on foundation every day.
- AApril4 minutes agoRated 1 out of 5 stars1 Star
The product doesbt gone out of the neddle head as it should and is worthless. Do not buy this product
- AGAllison G.Verified Buyer2 months agoRated 5 out of 5 stars5 Stars
This is my second time purchasing. The fine lines around my eyes and mouth are visibly reduced. It's completely painless and super easy to use at home. So worth the money.