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We’re confident you’ll love your results. If not, contact our team during your risk-free trial and we’ll handle the rest!
PDRN Micro-Infusion System
Inspired by professional skincare, this at-home micro-infusion system is powered by Salmon PDRN, known for it's skin-rejuvenating properties. The system uses ultra-fine touchpoints to help the PDRN and actives infuse beneath the surface. With consistent use, many people report their skin looks healthier, smoother, and more radiant over 6-12 weeks.
Suited to: All skin types, safe for sensitive skin
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SkinOS combines micro-infusion technology with PDRN — a molecule studied in Korean aesthetic clinics for its skin-rejuvenating properties. Unlike serums or creams that sit on the surface, our system helps deliver ingredients exactly where they’re needed.
Our micro-infusion device uses ultra-fine 0.5mm touchpoints to gently stamp the skin. These tiny needles create micro-channels that help active ingredients like PDRN (Salmon DNA) absorb more effectively.
As the skin responds, this process can help support smoother texture, improved hydration, and a more radiant look over time.
It’s a gentle method designed to enhance product absorption and help skin look refreshed with minimal downtime.
PDRN (Polydeoxyribonucleotide), often called Salmon DNA, is a well-studied ingredient known for its skin-supporting properties. Unlike regular serums that mainly sit on the surface, PDRN is designed to help skin feel smoother, look more hydrated, and support a healthier, more radiant appearance over time.
Many users notice improvements in the look of fine lines, uneven tone, and texture with consistent use, as PDRN helps skin appear refreshed and revitalised.
Each kit includes:
6 Week Supply: 3 sterile heads and 3 serum vials, providing 3 treatments.
12 Week Supply: 6 sterile heads and 6 serum vials, providing 6 treatments.
Each head and serum is intended for a single application every 1-2 weeks and should not be reused.
Using your SkinOS PDRN Micro-Infusion System is simple and designed for at-home convenience:
- Prep your skin – Start with a freshly cleansed face to ensure the serum absorbs properly.
- Fill the device – Pour the PDRN Renewal Serum into the micro-infusion device chamber. Leave the device upside down for 2-3 minutes to ensure the serum enters the needle head.
- Apply – Gently press the device onto your skin. The ultra-fine touchpoints create tiny channels, delivering the serum deep into the skin for maximum absorption. Work evenly across your face, focusing on areas with fine lines, dark spots, or uneven texture.
- Finish – Follow with your usual moisturizer or sunscreen.
Each session takes about 10–15 minutes, and for best results, we recommend using it once every 1–2 weeks.
Use every two weeks for best results. This allows your skin time to recover between sessions while letting the active ingredients work effectively. With consistent use, many people notice their skin looking smoother, fresher, and more radiant over time.
The micro-infusion device uses very fine micro touchpoints designed to minimize discomfort. Most users report a light prickling sensation but no pain.
You may experience mild redness or sensitivity post-use, which typically fades within a few hours. It’s safe to use at night so your skin can recover while you sleep.
Many people say their skin looks fresher and more radiant after the first few uses. Improvements in hydration, texture, and glow often become noticeable with regular use. Over time, users also report their skin looking smoother, more even-toned, and healthier overall.
Because micro-infusion supports the skin’s natural renewal process, results can continue to build gradually over time.
We ship worldwide from our trusted fulfillment partners. Orders are typically processed within 1 business day and delivered in 5–12 business days, depending on your location. You’ll receive tracking details as soon as your order is on its way.
You have 90 days to try our PDRN Micro-Infusion System and see the results for yourself. If you don’t notice any improvement, such as firmer, brighter, or more youthful-looking skin - simply contact us and we will gladly refund your money. To qualify, you’ll just need to provide before-and-after photos after each 2-week application within the 90-day period.
For full details or to start a return, contact our support team at support@useskinos.com

Real skin. Real change.

Day 1

Day 45
Visible Improvement
Fine lines & Wrinkles
“The change has been amazing… the wrinkles around my eyes are fading and my skin looks refreshed.”

Day 1

Day 60
Visible Improvement
Fine Lines, Firmness & Complexion
"My skin looks calmer, the redness has faded, and the area under my eyes feels so much brighter… and that’s just to start with."

Day 1

Day 90
Visible Improvement
Acne Scarring
“Week by week I could see my skin changing… the scars softened, the texture evened out, and now my cheeks look completely different.”

Day 1

Day 15
Visible Improvement
More Even Tone
“I’ve noticed my complexion looks brighter, my lines are less visible, and my skin feels tighter than before.”

Day 1

Day 45
Visible Improvement
Redness, Dark Spots, Texture
“My skin tone looks so much clearer, the redness has gone down, and the texture feels smoother every day.”
Individual results may vary. Everyone’s skin is unique and may respond differently. Results are not guaranteed. We offer a 90-day money back guarantee so you can experience it for yourself—love it, or return it hassle-free.
The science behind micro-infusion
Our micro-infusion device works by using tiny, 0.5mm gold-plated micro touchpoints to gently create micro-channels on the skin’s surface. This process allows active ingredients to absorb more effectively, while also supporting smoother texture and a refreshed appearance. Over time, consistent use may help improve the look of fine lines and overall skin radiance.
See visible improvements in 6-12 weeks

Fine lines & wrinkles
saw visibly smoother, firmer, less fine lines after consistent use.

Uneven skin tone
reported brighter, more even skin tone with reduced pigmentation.

Scars & texture
noticed softer, refined skin texture and diminished scarring.

Dehydration & dullness
experienced plumper, more radiant skin with lasting hydration.

The power of PDRN for your skin
Salmon PDRN isn’t your average skincare ingredient - it’s a compound used in regenerative science and advanced aesthetic treatments. Originally studied for wound healing, it works beneath the surface to support repair, encourage collagen production, and promote overall skin renewal.
Unlike surface-level ingredients like hyaluronic acid or niacinamide, PDRN is designed to work deeper, supporting lasting improvements in skin health, vitality, and radiance over time.
How to use your micro-infusion system

Prepare your device
Fill the chamber with one ampoule of serum, attach the needle head, and let it sit upside down for 1–2 minutes while you cleanse your face.

Infuse your skin
Gently stamp the device across your face, focusing on areas of concern. The precision 0.5mm gold-plated touchpoints create micro-channels to infuse active ingredients deep beneath the skin’s surface.

See your results
With consistent use, your skin can appear smoother, more radiant, and refreshed over time.
Powered by proven ingredients

Salmon PDRN
Helps support skin repair and renewal, improving the look of wrinkles, elasticity, and overall radiance.

Peptides
Support collagen and elastin, helping smooth texture and soften the appearance of fine lines and skin texture.

Niacinamide
Helps brighten the look of dark spots, even skin tone, and strengthen the skin barrier for a smoother feel.

Hyaluronic Acid
Delivers deep hydration to plump skin and reduce the appearance of dryness and dullness.
Why SkinOS is
the perfect choice.
Advanced skincare made simple, at home.
Frequently Asked Questions
How does the 90 day money back guarantee work?
You have 90 days to try our PDRN Micro-Infusion System and see how it works for your skin. If you don’t notice any improvement in your skin’s appearance, simply contact us and we’ll gladly refund your money. To qualify, you’ll just need to provide before-and-after photos after each application within the 90-day period.
How do I clean the device?
Once you’ve finished stamping your way to brighter and plumper skin, follow the below cleaning instructions:
- Twist off the head with the cap attached and safely dispose.
- Wash the chamber out with water and gentle cleanser.
- Let the device air dry completely, on a clean surface, before packing away.
- Open a brand new head and attach the head onto the device. Ensure hands are clean and don’t open the cap of the head.
When will I see improvements?
Many people say their skin looks fresher and more radiant after the first few uses. Improvements in hydration, texture, and glow often become noticeable with regular use. Over time, users also report their skin looking smoother, more even-toned, and healthier overall.
Because micro-infusion supports the skin’s natural renewal process, results can continue to build gradually over time.
Is it suitable for all skin types?
Yes — the PDRN Micro-Infusion System is suitable for all skin types, including normal, dry, oily, and combination. It’s designed to be gentle and effective, even for sensitive skin. If you have specific skin concerns such as eczema, rosacea, or severe acne, we recommend consulting with your dermatologist before purchasing to ensure it’s right for you.
Is there any down-time?
There’s very little downtime. You may notice mild redness or sensitivity right after application, similar to a light sunburn, which usually fades within 12–24 hours.
We recommend avoiding makeup, exfoliants, and strong active ingredients (like retinol, AHAs, BHAs, or vitamin C) for the first 24 hours to allow your skin to recover and maximize results. After that, you can return to your usual skincare routine.
Most people go back to daily activities immediately, with visible glow and minimal disruption.
Can you use it around the eyes and neck?
Yes, the SkinOS Micro-Infusion System can be used on the neck and décolletage, areas often associated with fine lines and uneven texture.
For the eye area, avoid direct use on the eyelids or too close to the lash line. Instead, focus on the under-eye and outer corners (crow’s feet), where the skin is thinner but can still benefit from infusion. Always use gentle pressure, follow instructions carefully, and patch test first.
How often can I do an application?
We recommend a PDRN Micro-Infusion application every 2 weeks for the best results!
How does it compare to Rejuran?
Rejuran is an in-clinic injectable treatment that also uses PDRN (Salmon DNA) to support skin rejuvenation. It requires medical administration, downtime, and costs hundreds of dollars per session.
The SkinOS PDRN Micro-Infusion System provides an at-home option inspired by the same active ingredient, PDRN. Using ultra-fine micro touchpoints, it helps active ingredients absorb beneath the skin’s surface without injections or long recovery times. This makes micro-infusion technology more accessible, convenient, and repeatable from home.
Can I use PDRN if I'm allergic to fish?
No — PDRN (Polydeoxyribonucleotide) is derived from salmon DNA. If you have a fish allergy, we do not recommend using this system, as it may trigger a reaction.
Your safety is our priority. If you have concerns about allergies or sensitivities, please consult your healthcare provider before use.
Do you ship internationally?
Yes, we ship worldwide. We have 5-12 day shipping times depending on your location.

