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We’re confident you’ll love your results. If not, contact our team during your risk-free trial and we’ll handle the rest!
PDRN Micro-Infusion System
Skincare that finally does what it promises.
SkinOS is the at-home PDRN micro-infusion device for women who've outgrown serums that disappear and routines that don't deliver. Visibly smoother, plumper, firmer skin in 12 weeks without the clinic, the cost, or the complexity.
Suited to: All skin types, including sensitive skin.
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Real skin. Real change.

Day 1

Day 45
Visible Improvement
Fine lines & Wrinkles
“The change has been amazing… the wrinkles around my eyes are fading and my skin looks refreshed.”

Day 1

Day 60
Visible Improvement
Fine Lines, Firmness & Complexion
"My skin looks calmer, the redness has faded, and the area under my eyes feels so much brighter… and that’s just to start with."

Day 1

Day 15
Visible Improvement
More Even Tone
“I’ve noticed my complexion looks brighter, my lines are less visible, and my skin feels tighter than before.”

Day 1

Day 90
Visible Improvement
Acne Scarring
“Week by week I could see my skin changing… the scars softened, the texture evened out, and now my cheeks look completely different.”

Day 1

Day 45
Visible Improvement
Redness, Dark Spots, Texture
“My skin tone looks so much clearer, the redness has gone down, and the texture feels smoother every day.”
Individual results may vary. Everyone’s skin is unique and may respond differently. Results are not guaranteed. We offer a 90-day money back guarantee so you can experience it for yourself—love it, or return it hassle-free.
Every Other Serum Just Sits on the Surface of Your Skin.
There comes a point when your skincare just stops showing up. Foundation settles into every line. The serum you swore by feels like it is just sitting there. Your shelf is full. Your skin doesn't bounce back like it used to.
This is not a product problem. As skin matures, its outer barrier becomes less efficient at absorbing what you put on top of it.
SkinOS uses ultra-fine surface touchpoints to create temporary micro-channels in the skin's surface, helping a PDRN-powered serum reach beyond the outer barrier. Where it can support smoother, plumper, healthier-looking skin over time.
Stronger than a serum. Gentler than a clinic.
Excellent · 1,000+ Reviews · ★★★★★
SkinOS Customer Transformations

Diana, 52
"Genuinely surprised by the difference"
"I'm 52 and my neck has been the worst part the last few years, all that crepey skin getting deeper and making me feel old every time I caught a glimpse of myself. Tried so many neck creams that did nothing. So i bought SkinOS. Did the full 3 months and the difference around my neck is really there. Just looks like myself but less tired. Husband even noticed."

Susan, 59
"My skin texture is just nicer"
These lines around my mouth have been driving me crazy. even with lipstick on they just settle in deeper and make me look so much older than I feel. So I figured I'd give SkinOS a try. Did 4 treatments and I genuinely cannot believe the difference around my mouth. The marionette lines are so much softer and my skin texture overall is just nicer too. So happy I tried this.

Linda, 69
"Softened so much, especially when I smile"
"Honestly at 69 I'd kind of accepted the lines on my face were just part of who I am now. Saw an ad for SkinOS and figured I had nothing to lose. The crows feet around my eyes have softened so much, especially when I smile. My cheeks look smoother too. I don't expect miracles at my age but this is the closest thing I've gotten. Have placed another order"

Karen, 58
"My skin overall just looks fresher"
"I'd been looking at this for a while before I bought it. Read every article and clinical study i could find on PDRN. I'm 58 and I don't throw money at skincare anymore unless I'm fairly sure it'll do something. After 3 months I can honestly say my under eyes look brighter and my skin overall just looks fresher. Forehead lines are still there but softer. Not a miracle but a real improvement. Will buy it again."

Linda, 69
"Made this much difference at home"
"The wrinkles around my mouth and jawline have been bothering me for years now. Every time I'd look in the mirror it just looked like everything was sliding south. Decided to try SkinOS after my sister bought it and went on about it for a month. After 3 months the lines around my mouth are so much softer and my jawline actually looks more defined. Genuinely surprised it made this much difference at home. So glad I bothered."
Stronger than a Serum. Less than an Injectable.
SkinOS works in two parts. Ultra-fine surface touchpoints create temporary micro-channels in the skin's outer layer. They're invisible, painless, and gone within hours. Through those channels, a PDRN-powered serum reaches the deeper layers where most topicals never make it.
PDRN (polydeoxyribonucleotide) is the same regenerative compound used in clinical skin-boosting treatments. It's known to support collagen, elastin, and skin repair at the cellular level.
More intentional than a serum. More private and gentler than a clinic appointment.
Why PDRN, and Why Now

A Studied Compound
PDRN is a compound traditionally derived from purified salmon DNA. It has been studied for decades in wound healing, tissue support, and aesthetic dermatology.

Used in Clinics Worldwide
In Korea and parts of Europe, PDRN injections are used in aesthetic clinics to support skin quality, texture, and hydration. Clinic sessions can cost thousands of dollars.

At Home, the Smart Way
SkinOS combines PDRN serum with at-home micro-infusion. The device helps the serum reach beyond the skin's outer surface, where most topical products never reach. Five minutes, every two weeks, in your bathroom.

Built for Mature Skin
Mature skin needs more than topical moisture. PDRN is one of the few studied ingredients specifically associated with supporting skin quality, hydration, and texture as skin's natural renewal slows down.
How to use your micro-infusion system

Prepare your device
Fill the chamber with one ampoule of serum, attach the needle head, and let it sit upside down for 1–2 minutes while you cleanse your face.

Infuse your skin
Gently stamp the device across your face, focusing on areas of concern. The precision 0.5mm gold-plated touchpoints create micro-channels to infuse active ingredients deep beneath the skin’s surface.

See your results
With consistent use, your skin can appear smoother, more radiant, and refreshed over time.
Powered by proven ingredients

Salmon PDRN
Helps support skin repair and renewal, improving the look of wrinkles, elasticity, and overall radiance.

Peptides
Support collagen and elastin, helping smooth texture and soften the appearance of fine lines and skin texture.

Niacinamide
Helps brighten the look of dark spots, even skin tone, and strengthen the skin barrier for a smoother feel.

Hyaluronic Acid
Delivers deep hydration to plump skin and reduce the appearance of dryness and dullness.
Frequently Asked Questions
How does micro-infusion work?
Our micro-infusion device uses ultra-fine 0.5mm touchpoints to gently stamp the skin. These tiny needles create micro-channels that help active ingredients like PDRN (Salmon DNA) absorb more effectively.
As the skin responds, this process can help support smoother texture, improved hydration, and a more radiant look over time.
It’s a gentle method designed to enhance product absorption and help skin look refreshed with minimal downtime.
What's included?
Each kit includes:
6 Week Supply: 3 sterile heads and 3 serum vials, providing 3 treatments.
12 Week Supply: 6 sterile heads and 6 serum vials, providing 6 treatments.
Each head and serum is intended for a single application every 1-2 weeks and should not be reused.
How quickly can I expect improvements?
Many people say their skin looks fresher and more radiant after the first few uses. Improvements in hydration, texture, and glow often become noticeable with regular use. Over time, users also report their skin looking smoother, more even-toned, and healthier overall.
Because micro-infusion supports the skin’s natural renewal process, results can continue to build gradually over time.
How does the 90 day money back guarantee work?
You have 90 days to try our PDRN Micro-Infusion System and see how it works for your skin. If you don’t notice any improvement in your skin’s appearance, simply contact us and we’ll gladly refund your money. To qualify, you’ll just need to provide before-and-after photos after each application within the 90-day period.
How do I clean the device?
Once you’ve finished stamping your way to brighter and plumper skin, follow the below cleaning instructions:
- Twist off the head with the cap attached and safely dispose.
- Wash the chamber out with water and gentle cleanser.
- Let the device air dry completely, on a clean surface, before packing away.
- Open a brand new head and attach the head onto the device. Ensure hands are clean and don’t open the cap of the head.
When will I see improvements?
Many people say their skin looks fresher and more radiant after the first few uses. Improvements in hydration, texture, and glow often become noticeable with regular use. Over time, users also report their skin looking smoother, more even-toned, and healthier overall.
Because micro-infusion supports the skin’s natural renewal process, results can continue to build gradually over time.
Is it suitable for all skin types?
Yes — the PDRN Micro-Infusion System is suitable for all skin types, including normal, dry, oily, and combination. It’s designed to be gentle and effective, even for sensitive skin. If you have specific skin concerns such as eczema, rosacea, or severe acne, we recommend consulting with your dermatologist before purchasing to ensure it’s right for you.
Is there any down-time?
There’s very little downtime. You may notice mild redness or sensitivity right after application, similar to a light sunburn, which usually fades within 12–24 hours.
We recommend avoiding makeup, exfoliants, and strong active ingredients (like retinol, AHAs, BHAs, or vitamin C) for the first 24 hours to allow your skin to recover and maximize results. After that, you can return to your usual skincare routine.
Most people go back to daily activities immediately, with visible glow and minimal disruption.
Can you use it around the eyes and neck?
Yes, the SkinOS Micro-Infusion System can be used on the neck and décolletage, areas often associated with fine lines and uneven texture.
For the eye area, avoid direct use on the eyelids or too close to the lash line. Instead, focus on the under-eye and outer corners (crow’s feet), where the skin is thinner but can still benefit from infusion. Always use gentle pressure, follow instructions carefully, and patch test first.
How often can I do an application?
We recommend a PDRN Micro-Infusion application every 2 weeks for the best results!
How does it compare to Rejuran?
Rejuran is an in-clinic injectable treatment that also uses PDRN (Salmon DNA) to support skin rejuvenation. It requires medical administration, downtime, and costs hundreds of dollars per session.
The SkinOS PDRN Micro-Infusion System provides an at-home option inspired by the same active ingredient, PDRN. Using ultra-fine micro touchpoints, it helps active ingredients absorb beneath the skin’s surface without injections or long recovery times. This makes micro-infusion technology more accessible, convenient, and repeatable from home.
Can I use PDRN if I'm allergic to fish?
No — PDRN (Polydeoxyribonucleotide) is derived from salmon DNA. If you have a fish allergy, we do not recommend using this system, as it may trigger a reaction.
Your safety is our priority. If you have concerns about allergies or sensitivities, please consult your healthcare provider before use.
Do you ship internationally?
Yes, we ship worldwide. We have 5-12 day shipping times depending on your location.

